TY - JOUR AU - Moerbeek, Mirjam AU - van Schie, Sander PY - 2016 DA - 2016/07/11 TI - How large are the consequences of covariate imbalance in cluster randomized trials: a simulation study with a continuous outcome and a binary covariate at the cluster level JO - BMC Medical Research Methodology SP - 79 VL - 16 IS - 1 AB - The number of clusters in a cluster randomized trial is often low. It is therefore likely random assignment of clusters to treatment conditions results in covariate imbalance. There are no studies that quantify the consequences of covariate imbalance in cluster randomized trials on parameter and standard error bias and on power to detect treatment effects. SN - 1471-2288 UR - https://doi.org/10.1186/s12874-016-0182-7 DO - 10.1186/s12874-016-0182-7 ID - Moerbeek2016 ER -