Fig. 1

Graphical representation of a joint model of a time-to-event submodel and K-multivariate longitudinal outcomes submodel. Square boxes denote observed data; circles denote unobserved (including random) terms. The black-dashed box indicates that covariates can be shared between both submodels. The red-dashed box indicates that the process W _i (t) and the random effects, b _i , are correlated, which gives rise to the joint model. T _i is the failure time, which may or may not be observed, in which case a censoring time is observed. All other notation is defined as above