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Table 2 Characteristics of the update methods and number of parameters estimated in the case study of prediction of prostate cancer at biopsy

From: Improving prediction models with new markers: a comparison of updating strategies

Method

Data required

Nr. Parameters estimated

Nr. Parameters estimated in case study

Original Model

No data

0

0

Model Revision with extension

Marker set

p + m + 1

5

Model Revision with shrinkage

Marker set

p + m + 1

5

Recalibration and extension

Marker set

m + 2

3

CLR

Marker set

2 m (p + 1) + m (m + 1)

10

CLR simple

Marker set

m (p + 2) + m (m + 1)/2

6

Imputation

Development and marker

p + m + 1

5

  1. p: number of predictors in original model, m: number of markers