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BMC Medical Research Methodology

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Rationale and design of mDOT-HuA study: a randomized trial to assess the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemia in Tanzania

  • Abel Makubi1, 2, 3Email author,
  • Philip Sasi1,
  • Mariam Ngaeje2,
  • Enrico M. Novelli4,
  • Bruno P. Mmbando5,
  • Mark T. Gladwin4, 6 and
  • Julie Makani1, 2, 3, 7
BMC Medical Research MethodologyBMC series – open, inclusive and trusted201616:140

https://doi.org/10.1186/s12874-016-0245-9

Received: 1 July 2016

Accepted: 13 October 2016

Published: 18 October 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
1 Jul 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 3
Submitted Manuscript version 3
Publishing
13 Oct 2016 Editorially accepted
18 Oct 2016 Article published 10.1186/s12874-016-0245-9

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
School of Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
(2)
Muhimbili Sickle cell Programme, Dar es Salaam, Tanzania
(3)
Muhimbili National Hospital, Dar es Salaam, Tanzania
(4)
Department of Medicine, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, USA
(5)
National Institute of Medical Research, Tanga, Tanzania
(6)
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA
(7)
Nuffield Department of Clinical Medicine, University of Oxford, London, UK

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