Skip to content


  • Study protocol
  • Open Access
  • Open Peer Review

This article has Open Peer Review reports available.

How does Open Peer Review work?

Rationale and design of mDOT-HuA study: a randomized trial to assess the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemia in Tanzania

  • Abel Makubi1, 2, 3Email author,
  • Philip Sasi1,
  • Mariam Ngaeje2,
  • Enrico M. Novelli4,
  • Bruno P. Mmbando5,
  • Mark T. Gladwin4, 6 and
  • Julie Makani1, 2, 3, 7
BMC Medical Research MethodologyBMC series – open, inclusive and trusted201616:140

Received: 1 July 2016

Accepted: 13 October 2016

Published: 18 October 2016

Back to article

Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
1 Jul 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 3
Submitted Manuscript version 3
13 Oct 2016 Editorially accepted
18 Oct 2016 Article published 10.1186/s12874-016-0245-9

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

School of Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
Muhimbili Sickle cell Programme, Dar es Salaam, Tanzania
Muhimbili National Hospital, Dar es Salaam, Tanzania
Department of Medicine, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, USA
National Institute of Medical Research, Tanga, Tanzania
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA
Nuffield Department of Clinical Medicine, University of Oxford, London, UK