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BMC Medical Research Methodology

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Conducting a large, multi-site survey about patients’ views on broad consent: challenges and solutions

  • Maureen E. Smith1Email author,
  • Saskia C. Sanderson2, 3,
  • Kyle B. Brothers4,
  • Melanie F. Myers5,
  • Jennifer McCormick6,
  • Sharon Aufox1,
  • Martha J. Shrubsole7,
  • Nanibaá A. Garrison8,
  • Nathaniel D. Mercaldo7,
  • Jonathan S. Schildcrout7,
  • Ellen Wright Clayton7,
  • Armand H. Matheny Antommaria5,
  • Melissa Basford7,
  • Murray Brilliant9,
  • John J. Connolly10,
  • Stephanie M. Fullerton11,
  • Carol R. Horowitz2,
  • Gail P. Jarvik11,
  • Dave Kaufman12,
  • Terri Kitchner9,
  • Rongling Li12,
  • Evette J. Ludman13,
  • Catherine McCarty14,
  • Valerie McManus9,
  • Sarah Stallings7,
  • Janet L. Williams15 and
  • Ingrid A. Holm16
BMC Medical Research MethodologyBMC series – open, inclusive and trusted201616:162

Received: 13 May 2016

Accepted: 11 November 2016

Published: 24 November 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
13 May 2016 Submitted Original manuscript
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
11 Nov 2016 Editorially accepted
24 Nov 2016 Article published 10.1186/s12874-016-0263-7

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

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Authors’ Affiliations

Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, USA
Icahn School of Medicine at Mount Sinai, New York, USA
University College London, London, UK
University of Louisville School of Medicine, Louisville, USA
Cincinnati Children’s Hospital Medical Center, Cincinnati, USA
Penn State College of Medicine, Hershey, USA
Vanderbilt University Medical Center and Vanderbilt University, Nashville, USA
Seattle Children’s Research Institute, Seattle, USA
Marshfield Clinic Research Foundation, Marshfield, USA
The Children’s Hospital of Philadelphia, Philadelphia, USA
University of Washington, Seattle, USA
National Human Genome Research Institute, National Institutes of Health, Bethesda, USA
Group Health Research Institute, Seattle, USA
Essentia Institute of Rural Health, Duluth, USA
Geisinger Health System, Danville, USA
Boston Children’s Hospital, Harvard Medical School, Boston, USA