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Table 1 Distributions specifying activity durations and diagnostic characteristics for the current decentralised model

From: Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

Activity duration (minutes)

  

Model parameter

Distribution: type

Parameters

Time from stroke onset to call for help

Continuous empirical

   

Route 1

 

Left bound

Right bound

Frequency

0

5

39

5

10

21

10

15

15

15

30

35

30

45

33

45

60

14

60

120

40

120

180

16

180

240

10

240

480

9

480

2880

230

Route 2

 

0

5

1

5

10

1

10

15

1

480

2880

15

Route 3

 

0

60

9

60

120

17

120

180

3

180

240

4

240

480

2

480

2880

286

Delay first responder

911 call

Uniform

Min (1.00), Max (2.00)

GP consult by telephone

Uniform

Min (2.00), Max (5.00)

GP consult by visit

Triangle

Mode (40.00), Min (10.00), Max (30.00)

EMS

Response time

A1

Continuous empirical

Left bound

Right bound

Frequency

0

5

53

5

10

145

10

15

85

15

20

23

20

25

2

25

30

1

30

35

0

35

40

2

A2

Gamma

Alpha (3.36), Beta (4.22)

B

Beta

Alpha 1 (0.69), Alpha 2 (0.53), a (8.92), b (59.33)

Time spent on scene

A1

Continuous empirical

Left bound

Right bound

Frequency

0

5

3

5

10

45

10

15

106

15

20

87

20

25

39

25

30

13

30

35

8

35

40

3

40

45

4

45

60

2

A2

Lognormal

Mean (15.24), St. dev. (7.67)

B

Lognormal

Mean (15.12), St. dev. (8.14)

Transport time

A1

Beta

Alpha1 (1.69), Alpha2 (4.16), a (39.66), b (0.62)

A2

Gamma

Alpha (5.53), Beta (2.51)

B

Beta

Alpha 1 (1.07), Alpha 2 (1.41), a (0.02), b (31.61)

Time to neurological consultation

Continuous empirical

Left bound

Right bound

Frequency

0

0

79

0

1

5

1

2

13

2

5

39

5

10

30

10

15

19

15

30

12

30

72

19

Time to neuroimaging (CT) examination

Continuous empirical

Left bound

Right bound

Frequency

0

5

9

5

10

23

10

15

36

15

20

29

20

25

32

25

30

29

30

35

21

35

40

11

40

45

11

45

50

3

50

55

2

55

60

7

85

90

3

90

135

2

Time to laboratory examination

Continuous empirical

Left bound

Right bound

Frequency

0

0

61

0

10

5

10

15

8

15

20

14

20

25

18

25

30

16

30

35

14

35

40

20

40

45

18

45

50

12

50

80

16

Treatment decision

Triangle

Mode (10), Min (5), Max (20)

tPA mixing

Constant

5

Diagnostics

 Choice of route

Discrete empirical

Value

Frequency

 1. EMS transport

 

1

462

 2. In-hospital

 

2

18

 3. Self-transport

 

3

321

 Choice first responder

Discrete empirical

Value

Frequency

 1. 911 call

 

1

184

 2. GP consult by phone

 

2

56

 3. GP consult by visit

 

3

126

 EMS transport, level of urgency

Discrete empirical

Value

Frequency

 911 call

   

 1. A1

 

1

92

 2. A2

 

2

7

 3. B

 

3

1

 GP consult by telephone

 1. A1

 

1

60

 2. A2

 

2

39

 3. B

 

3

1

 GP consult by visit

 1. A1

 

1

47

 2. A2

 

2

42

 3. B

 

3

11

  1. Route 1, 2, and 3 indicate patients transported by emergency medical services, those suffering a stroke in the hospital, and patients arriving by self transport, respectively; GP General practitioner, EMS Emergency medical services; A1, A2, B indicate normative values for ambulance arrival within 15, 30, and > 30 min from the 911 call until arrival at the location of the patients, respectively; CT, computed tomography; tPA, tissue plasminogen activator. Neurological examination, neuroimaging, and laboratory examination are considered parallel activities