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Table 3 Results simulation experiments

From: Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

Scenario

tPA rate (95% CI)

tPA 0–90 min

tPA 90–180 min

tPA 180–270 min

mRS 0-1a

OTT minutes (95% CI)

Extra healthy life days (95% prediction interval)b

0. Current decentralised stroke care

14.4% (13.7%–15.1%)

14.3%

70.5%

15.2%

14.7%

134 (131–136)

 

1. Optimising all 9 Community hospitals

22.4% (21.6%–23.2%)

27.5%

62.0%

10.5%

26.6%

119 (117–127)

27.0 (13.5–40.5)

2. Centralisation (4 stroke centers)

21.8% (21.0%–22.7%)

25.1%

63.2%

11.7%

25.3%

122 (120–124)

21.6 (10.8–32.4)

3. Centralisation (2 stroke centres)

21.2% (20.4%–22.0%)

21.6%

66.6%

11.9%

23.8%

125 (123–127)

16.2 (8.1–24.3)

  1. tPA indicates tissue plasminogen activator; CI, confidence interval; mRS, modified rankin scale; OTT, onset treatment time
  2. aIndicates the proportion of patients with excellent functional outcome (mRS 0–1) ascribed with thrombolysis treatment [12]
  3. bIndicates the number of additional days in healthy life per minute reduction in OTT [11]