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Table 5 Results of the normalization process for three institutional studies

From: Leveraging the EHR4CR platform to support patient inclusion in academic studies: challenges and lessons learned

Outcomes aXa DERENEDIAB EWING 2008 Total
Cases Controls
ELIGIBILITY CRITERIA
 Criteria before normalization 20 12 20 15 67
 Complex criteria 15 (75%) 10 (83%) 15 (75%) 10 (67%) 50 (75%)
 Unchanged criteria 9 (45%) 8 (67%) 10 (50%) 9 (60%) 36 (54%)
 Criteria after normalization 20 (100%) 11 (92%) 20 (100%) 15 (100%) 66 (99%)
MEDICAL CONCEPTS
 Individual medical concepts identified in free-text eligibility criteria 45 16 39 14 114
 Medical concepts mapped to EHR4CR terminologiesa 30 (67%) 15 (94%) 38 (97%) 9 (64%) 92 (81%)
 Medical concepts mapped from EHR4CR terminologies to local terminologies 30 (67%) 15 (94%) 34 (87%) 7 (50%) 86 (75%)
 Free-text medical concepts present and structured in the local CDW/EHR 30 (67%) 16 (100%) 34 (87%) 9 (64%) 89 (78%)
 Free-text medical concepts present and unstructured in the local CDW/EHR 15 (33%) 0 (0%) 4 (10%) 4 (29%) 23 (20%)
 Free-text medical concepts missing in the local CDW/EHR 0 (0%) 0 (0%) 1 (3%) 1 (7%) 2 (2%)
FINAL COMPUTABLE CRITERIA 14 8 17 12 51
  1. a medical concepts that correspond to unstructured data in local CDW/EHR were not mapped to EHR4CR terminologies