Skip to main content

Table 4 Modeling the risk of cardiac events. Estimate of the regression coefficients with SE in the parenthesis

From: Performance of Firth-and logF-type penalized methods in risk prediction for small or sparse binary data

 

Modeling the risk of MI

 

MLE

FIRTH

logF(1,1)

logF(2,2)

RIDGE

Dobutamine EF

-0.0503

-0.0492

-0.0508

-0.0513

-0.0413

 

(0.0183)

(0.0178)

(0.0183)

(0.0182)

(0.0161)

Positive DSE

1.272

1.241

1.185

1.109

0.994

 

(0.549)

(0.531)

(0.533)

(0.518)

(0.469)

Hist. of HT

1.115

0.923

0.973

0.866

0.657

 

(0.789)

(0.716)

(0.716)

(0.662)

(0.542)

Intercept

-1.253

-1.028

-1.057

-0.901

-1.243

 

(1.351)

(1.284)

(1.307)

(1.275)

(1.132)

 

Modeling the risk of CABG

Dobutamine EF

-0.0634

-0.0506

-0.0518

-0.0523

-0.0420

 

(0.0181)

(0.0177)

(0.0181)

(0.0181)

(0.0161)

Positive DSE

1.568

1.190

1.137

1.068

0.971

 

(0.551)

(0.529)

(0.531)

(0.516)

(0.468)

Intercept

0.272

-0.224

-0.206

-0.145

-0.683

 

(1.122)

(1.120)

(1.140)

(1.131)

(1.029)

 

Modeling the risk of PTCA

Positive DSE

0.825

0.820

0.770

0.722

0.579

 

(0.498)

(0.481)

(0.483)

(0.470)

(0.409)

Base EF

-0.0381

-0.0375

-0.0389

-0.0396

-0.0306

 

(0.0204)

(0.0198)

(0.0202)

(0.0201)

(0.0168)

Hist. of MI

1.168

1.125

1.118

1.072

0.867

 

(0.533)

(0.517)

(0.515)

(0.499)

(0.412)

Hist of PTCA

1.304

1.310

1.211

1.127

1.087

 

(0.617)

(0.591)

(0.602)

(0.588)

(0.555)

Intercept

-1.754

-1.661

-1.646

-1.548

-1.809

 

(1.184)

(1.151)

(1.167)

(1.153)

(0.968)

 

Modeling the risk of cardiac death

Positive DSE

1.084

1.061

1.026

0.974

0.873

 

(0.489)

(0.474)

(0.478)

(0.467)

(0.436)

Hist. of DM

1.083

1.047

1.025

0.973

0.784

 

(0.495)

(0.480)

(0.481)

(0.468)

(0.419)

Age

0.0347

0.0328

0.0344

0.0342

0.0229

 

(0.0240)

(0.0236)

(0.0238)

(0.0236)

(0.0188)

Intercept

-6.040

-5.783

-5.965

-5.899

-4.960

 

(1.787)

(1.750)

(1.769)

(1.753)

(1.379)

Positive DSE

1.064

1.045

1.047

0.989

0.940

 

(0.332)

(0.327)

(0.327)

(0.264)

(0.248)

Dobutamine EF

-0.0381

-0.0372

-0.0384

-0.0364

-0.0333

 

(0.0131)

(0.0128)

(0.0130)

(0.0103)

(0.00941)

 

Modeling the risk of any cardiac event

Rest WMA

-0.779

-0.758

-0.755

-0.839

-0.762

 

(0.429)

(0.421)

(0.419)

(0.336)

(0.293)

Hist. of HT

0.823

0.781

0.794

0.728

0.632

 

(0.393)

(0.384)

(0.384)

(0.302)

(0.276)

Intercept

0.107

0.115

0.151

0.0102

-0.0980

 

(0.833)

(0.818)

(0.829)

(0.655)

(0.611)