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Table 1 Impact of propensity score adjustment for development cohort

From: The feasibility of matching on a propensity score for acupuncture in a prospective cohort study of patients with chronic pain

 

Unadjusted for propensity score

Adjusted for decile of propensity score

Started Acupuncture

(n = 952)

Did Not Start Acupuncture

(n = 59,564)

Standardized differencea

Standardized differencea

Propensity score characteristicsb

 Opioid therapy plan

28.8%

17.8%

0.261

0.023

 Physical therapy past 30 days

16.3%

15.1%

0.032

−0.008

 Physical therapy past 31–180 days

25.0%

11.1%

0.368

0.018

 Physical therapy past 181–365 days

24.5%

12.1%

0.324

0.016

 Nonspecific chronic pain

29.6%

14.4%

0.373

0.031

 Substance abuse

4.6%

4.1%

0.028

0.003

 Sleep problem

23.6%

14.6%

0.232

0.016

 History of tobacco use

14.2%

12.9%

0.036

0.000

 Anxiety

23.7%

15.6%

0.206

0.017

 Pain treatment procedure

38.2%

22.5%

0.344

0.020

 Pain diagnosis procedure

65.3%

52.5%

0.261

0.011

 Pain medication

81.2%

65.0%

0.370

0.008

 Age (years)

53.8 (14.0)

55.2 (15.0)

−0.097

−0.008

 Number of outpatient visits

15.9 (10.8)

10.4 (10.1)

−0.543

0.011

 Months since cohort entry

29.1 (14.7)

25.2 (15.6)

−0.246

0.010

 Ambulatory Charlson score

1.8 (2.2)

1.9 (2.1)

−0.036

−0.006

Demographic Characteristics

 Female

72. 8%

62.0%

0.232

0.146

 White

91.2%

91.9%

−0.023

−0.033

 Hispanic

5.4%

7.7%

−0.091

−0.093

Medical and Psychiatric Comorbidities

 Depression

21.5%

15.8%

0.148

0.014

Types of Nonmalignant Chronic Pain (NCP)

 Back and/or neck pain

80.6%

55.9%

0.539

0.407

 Joint pain (including osteoarthritis)

79.3%

79.3%

0.001

−0.114

 Fibromyalgia/other myofascial pain

30.1%

11.8%

0.461

0.257

 Headaches

18.0%

12.0%

0.167

0.077

 Neuropathy

1.5%

1.5%

−0.001

0.011

 Temporomandibular disorders

5.0%

3.0%

0.105

0.046

 Carpal tunnel syndrome

6.5%

5.8%

0.028

−0.016

 Abdominal pain

6.3%

4.8%

0.068

−0.018

 Other NCP

5.8%

6.6%

−0.034

−0.057

 Two of above NCP types

81.1%

60.6%

0.457

0.224

Pharmacotherapy

 Any use of an opioid

19.9%

11.8%

0.223

0.025

 Opioid morphine equivalent dose (MED)

0.3 (1.7)

0.2 (0.9)

0.122

−0.012

  ≥ 120 MED

7.9%

4.5%

0.141

−0.007

Mental health related

 Any antidepressant use

47.6%

35.4%

0.247

0.036

 Any anxiolytic use

33.1%

21.2%

0.270

0.041

 Any benzodiazepine use

35.4%

21.1%

0.321

0.067

  1. aStandardized difference expressed as (difference in means)/(pooled standard deviation) for continuous measures and as 2*(arcsin(√P1)-arcsin(√P2)) for binary data. For propensity score decile adjusted data, standardized differences calculated using same standard deviation as for unadjusted data in order to make comparison of standardized differences with and without adjustment more meaningful
  2. bContinuous data expressed as mean (standard deviation)