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Table 2 Bounds on sufficient-cause interactions in a case-control study on lung cancer risk (Example 2)

From: Sharp bounds on sufficient-cause interactions under the assumption of no redundancy

 

Case Number

Control Number

Case-Control Odds

Relative prevalence of sufficient-cause interaction

95% LCLc

LBc

Specific (ADPRT a, XRCC1 b)

 (Val/Val, Arg/Arg)

157

186

0.8441

0.0000

0.0000

 (Val/Val, Arg/Gln)

124

142

0.8732

0.0000

0.0000

 (Val/Val, Gln/Gln)

26

31

0.8387

0.0000

0.0000

 (Val/Ala, Arg/Arg)

273

286

0.9545

0.0000

0.0000

 (Val/Ala, Arg/Gln)

180

183

0.9836

0.0000

0.0000

 (Val/Ala, Gln/Gln)

56

53

1.0566

0.0000

0.0000

 (Ala/Ala, Arg/Arg)

105

77

1.3636

0.0000

0.0000

 (Ala/Ala, Arg/Gln)

59

55

1.0727

0.0000

0.0000

 (Ala/Ala, Gln/Gln)

20

5

4.0000

0.0000

0.5221

Global

1000

1018

0.9823

0.0784

0.2471

  1. a ADPRT: adenosine diphosphate ribosyltransferase
  2. b XRCC1: X-ray repair cross-complementing group 1
  3. c LCL lower confidence limit for the lower bound, LB lower bound