Skip to main content
Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Robust estimation of the expected survival probabilities from high-dimensional Cox models with biomarker-by-treatment interactions in randomized clinical trials

Fig. 2

Graphical illustration of the expected survival probability at a given timepoint against the treatment-effect modifying ore. Expected survival probability against the treatment-effect modifying score \( \widehat{\eta} \) in the setting of: no prognostic biomarker identified and one (a) or multiple (b) treatment-effect modifiers; multiple prognostic markers and treatment-modifiers in the lowest (c) and higher (d) prognostic risk group. Dot: point estimate, vertical line: 95% pointwise confidence interval, solid curves: average smoothed splines for point estimates, dashed curves: average smoothed splines for confidence bounds. Graphical illustrations are coming from several selected models based on a simulated dataset from the scenario 6

Back to article page