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Table 4 EffTox posterior beliefs after 3TTT

From: Implementing the EffTox dose-finding design in the Matchpoint trial

 

Dose 1

Dose 2

Dose 3

Dose 4

Utility

-0.489

-0.534

-0.777

-0.817

Pr(\({\pi }_{E} > \underline {{\pi }}_{E}\))

0.079

0.037

0.060

0.200

Pr(\({\pi }_{T} < \overline {{\pi }}_{T}\))

0.919

0.758

0.051

0.005

Admissible under p E =0.05, p T =0.05

1

0

1

0

Admissible under p E =0.03, p T =0.05

1

1

1

0

  1. The values for p E and p T determine the admissible doses