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Table 4 Results of the effect of rosiglitazone on hepatocellular carcinoma based on real data from the Korean National Health Insurance Database

From: Statistical methods for elimination of guarantee-time bias in cohort studies: a simulation study

Cumulative dose

Cox regression

Time-dependent Cox regression

Landmark analyses

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

p-value

Low

0.852

0.420

1.731

0.659

1.155

0.568

2.347

0.691

1.059

0.332

3.374

0.923

Moderate

0.710

0.315

1.602

0.410

0.983

0.435

2.220

0.967

0.775

0.189

3.167

0.722

High

0.443

0.218

0.899

0.024

0.778

0.381

1.587

0.490

0.812

0.295

2.233

0.687

  1. HR Hazard ratio, 95% CI 95% Confidence interval