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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity

Fig. 1

Mean and estimated dose response of mean change in DAS28 scores from baseline using Bayesian Emax and NDLM models. The mean changes in DAS28 score between the doses were connected with a straight line in solid blue lines; the data are for illustration purpose so the error bars are not presented. Emax model is displayed as red dash/dotted line and NDLM model as green dotted line

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