From: Patients’ beliefs regarding informed consent for low-risk pragmatic trials
Variable | Overall, % (n = 338) | Drug pRCT, % | Dose-timing pRCT, % | ||
---|---|---|---|---|---|
Written consent vs General notification (n = 85) | Written consent vs Verbal consent (n = 85) | Written consent vs General notification (n = 85) | Written consent vs Verbal consent (n = 83) | ||
Recommended written consent, preferred written consent | 70.4 | 62.4 | 81.2 | 51.8 | 86.7 |
Recommended written consent, preferred alternative option | 3.8 | 5.9 | 1.2 | 8.2 | 0.0 |
Recommended alternative option, preferred written consent | 3.6 | 7.1 | 3.5 | 3.5 | 0.0 |
Recommended alternative option, preferred alternative option | 22.2 | 24.7 | 14.1 | 36.5 | 13.3 |
p = 0.042 | p < 0.001 | ||||
Same personal preference and recommendation to the REC (Consistent responses) | 92.6 | 87.1 | 95.3 | 88.3 | 100.0 |
p = 0.051 | p = 0.001 | ||||
Personal preference and/or recommendation alternative option | 92.6 | 37.6 | 18.8 | 48.2 | 17.3 |
p = 0.005 | p < 0.001 |