Systematic Reviews used for estimating trial effectiveness | Pragmatic RCTs used for estimating uptake | |||
---|---|---|---|---|
Intervention | Clinical population | Outcome | Clinical population | Recruitment of clinicians |
Delayed prescribing [25] | People patients of all ages with upper respiratory tract infection | Antibiotic use (i.e. prescriptions filled) | Adults with acute cough, for whom the physician intended to prescribe antibiotics [16] | 22/61 practices approached actually participated. 48/92 GPs recruited patients to the trial (range = 1–25 per GP). |
Procalcitonin [26] | Adults with an acute respiratory infection (including lower respiratory infection such as pneumonia). | Antibiotics prescribed | Adults with an acute respiratory infection, for whom the physician intended to prescribe antibiotics [17] | 53/345 eligible primary care physicians in 2 cantons in northwest Switzerland actually participated |
CRP [27] | People of all ages with acute respiratory infection (including lower respiratory infection such as pneumonia) | Antibiotics prescribed | People of all ages with respiratory Infections (median age = 37 years [18]) | 35/125 GPs in single-handed practices in the County of Funen actually participated |
Shared decision making [28] | People of all ages with acute respiratory infection (including lower respiratory infection such as pneumonia) | Antibiotics prescribed, dispensed or decision to use | Adults with acute respiratory infection. [19] | 45/345 eligible GPs in two cantons, Basel-Stadt and Aargau actually participated. |
People of all ages with acute cough (mean age = 42 years [20] | 101/2036 GPs from 9 regions in North-Rhine and Westphalia-Lippe actually participated | |||
People of all ages with respiratory Infections (71% adults) [21] | 4/24 Family Medicine Groups (FMGs) in Quebec actually participated. Within the participating FMGs, 33/42 FPs participated |