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Table 9 Results of the Case Study

From: A comparison of estimators from self-controlled case series, case-crossover design, and sequence symmetry analysis for pharmacoepidemiological studies

Days of risk Methods
(Effect measures)
Point estimates
(Ratio scale)
95% CI
15 SCCS (IRR) 3.54 3.05–4.11
  CCO (OR) 4.38 2.81–6.82
  SSA (ASR) 2.61 1.78–3.84
30 SCCS (IRR) 2.65 2.33–3.00
  CCO (OR) 3.88 2.65–5.69
  SSA (ASR) 1.98 1.44–2.72
45 SCCS (IRR) 2.23 1.99–2.51
  CCO (OR) 3.23 2.30–4.53
  SSA (ASR) 1.75 1.32–2.34
  1. Abbreviations ASR Adjusted sequence ratio, CCO Case-crossover, CI Confidence interval, IRR Incident rate ratio, OR Odds ratio, SCCS Self-controlled case series, SSA Sequence symmetry analysis