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Table 1 Demographic table for training and validation HCV-related cirrhosis cohorts

From: Evaluating screening approaches for hepatocellular carcinoma in a cohort of HCV related cirrhosis patients from the Veteran’s Affairs Health Care System

 

Training cohort

Validation cohort

 

Controls

HCC cases

Controls

HCC cases

N

5611

451

5611

451

Age at baseline (years)

52.87 (7.28)

54.67 (7.78)

52.93 (7.39)

54.89 (7.49)

Male

5498 (97.99%)

449 (99.56%)

5501 (98.04%)

447 (99.11%)

Female

113 (2.01%)

2 (0.44%)

110 (1.96%)

4 (0.89%)

Race

    

White

1954 (34.82%)

173 (38.36%)

2034 (36.25%)

171 (37.92%)

Black

623 (11.10%)

54 (11.97%)

576 (10.27%)

60 (13.30%)

Other/Unknown

3034 (54.07%)

224 (49.67%)

3001 (53.48%)

220 (48.78%)

Number of AFP tests

    

1

1598 (28.48%)

116 (25.72%)

1598 (28.48%)

138 (30.60%)

2

1297 (23.12%)

119 (26.39%)

1240 (22.10%)

106 (23.50%)

3-4

1480 (26.38%)

119 (26.39%)

1524 (27.16%)

120 (26.61%)

> 4

1236 (22.03%)

97 (21.51%)

1249 (22.26%)

87 (19.29%)

Months between AFP tests

11.67 (11.00)

10.30 (10.10)

11.83 (11.26)

10.93 (10.89)

Baseline AFP in log2(ng/ml)

2.92 (1.55)

4.72 (2.78)

2.95 (1.57)

4.57 (2.95)

Baseline ALT in log2(ng/ml)

6.14 (1.03)

6.31 (0.91)

6.16 (1.05)

6.35 (0.88)

Baseline PLT in 1000’s

147.97 (78.88)

123.50 (66.06)

148.51 (78.83)

127.97 (76.08)

  1. For continuous variables we report means and standard deviations in parenthesis and for categorical variables we report the number in each group and percentages in parenthesis. Baseline was defined to be the date of the first AFP test