BMC Medical Research Methodology

Table 2 Estimated numbers of required subjects for 2, 3, 4 and 5 observations with ICC = 0.2

From: Sample size determination for mediation analysis of longitudinal data

Observations
	2			3			4			5
Effect size	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap
SS	408	330	341	291	244	234	239	204	201	201	169	175
SH	301	282	283	231	226	230	201	185	190	177	163	160
SM	294	287	279	226	220	218	191	188	185	163	166	170
SL	282	267	278	223	213	211	188	182	182	166	163	164
HS	240	206	224	166	137	139	129	107	107	108	89	84
HH	120	97	104	87	72	79	71	59	58	61	53	60
HM	95	87	90	74	65	68	61	56	60	56	49	52
HL	88	85	85	72	65	70	61	57	54	51	49	48
MS	213	194	202	148	138	141	112	102	111	90	81	85
MH	81	68	73	59	49	53	47	39	37	39	32	30
MM	56	46	50	40	33	33	34	27	28	28	25	23
ML	47	38	37	32	31	28	29	27	23	25	24	24
LS	215	189	204	136	136	140	105	103	108	85	82	85
LH	66	60	65	45	39	40	36	32	34	30	26	28
LM	38	32	33	27	24	24	21	18	18	19	16	14
LL	25	22	22	19	17	15	16	14	12	14	12	13

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ISSN: 1471-2288

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