BMC Medical Research Methodology

Table 4 Estimated numbers of required subjects for 2, 3, 4 and 5 observations with ICC = 0.6

From: Sample size determination for mediation analysis of longitudinal data

Observations
	2			3			4			5
Effect size	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap
SS	551	467	477	438	378	385	400	326	333	351	326	326
SH	451	426	453	376	369	370	363	349	350	332	326	334
SM	451	438	451	380	377	380	357	346	351	326	323	333
SL	454	444	445	385	376	380	344	326	340	326	313	324
HS	289	234	239	200	171	179	171	136	157	145	120	127
HH	156	132	130	127	111	122	111	101	108	104	93	96
HM	142	125	132	115	111	113	107	102	105	100	98	98
HL	133	131	127	115	111	112	102	97	97	100	97	99
MS	226	194	202	157	145	148	129	108	118	106	88	85
MH	99	80	91	76	62	73	63	52	60	57	48	52
MM	72	62	70	61	51	53	54	47	48	49	46	48
ML	63	59	61	53	52	52	49	49	49	47	46	46
LS	211	201	204	138	132	135	117	105	108	91	79	87
LH	72	62	65	52	45	49	43	36	38	37	31	32
LM	45	38	39	35	29	34	30	24	28	26	23	24
LL	33	31	32	28	24	25	25	24	25	23	21	23

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ISSN: 1471-2288

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