Fig. 4From: Advantages of a multi-state approach in surgical research: how intermediate events and risk factor profile affect the prognosis of a patient with locally advanced rectal cancera, b Dynamic prediction of 5-year survival. The plots show time-dependent predictions of survival at 5Â years after commencement of CTx for the high risk patient (a) and for the low risk one (b) after the completion of the 12Â months CTx and the development of a DM 2Â years after start of CTx. Dashed curves indicate what the 5-year survival probability would have been without DMBack to article page