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Table 2 Median reduction to MSE, in percentage, for covariates which improved the MSE in the onset-anchored model. The inter-quartile range (IQR) for the percent reduction as well as average difference in DIC is shown as well

From: Using an onset-anchored Bayesian hierarchical model to improve predictions for amyotrophic lateral sclerosis disease progression

Covariate Name Median % MSE reduction (negative values signify an increase to the MSE) IQR for % MSE reduction Mean DIC adjustment (larger values result in larger DIC)
Onset Time 0.0174 0.027 2.8
FVC: Subject Liters (slope) 0.0095 0.02 −3.5
Q1: Speech (slope) 0.0081 0.0187 0.8
Diagnosis Time 0.0059 0.0183 −2.1
Q7: Turning in Bed(slope) 0.0052 0.0182 −3.5
Q8: Walking (slope) 0.0052 0.0254 −2.2
AST (slope) 0.0043 0.0179 −0.3
Q5: Cutting (slope) 0.0043 0.0202 −1.5
Q6: Dressing/Hygiene (slope) 0.0039 0.0223 −1.9
ALT (slope) 0.0034 0.0166 0.1
Q2: Salivation (slope) 0.0032 0.0195 1.7
Q9: Climbing Stairs (slope) 0.003 0.0232 −2
AST (intercept) 0.0028 0.0162 0.8
FVC: Percent Normal (slope) 0.0025 0.0225 −3.4
Race 0.0021 0.0156 −0.1
ALT (intercept) 0.0021 0.0182 −0.7
Bilirubin Total (slope) 0.0019 0.0196 −0.5
Respiratory Rate (intercept) 0.0017 0.0146 0.3
Q2: Salivation (intercept) 0.0013 0.0203 −1.4
Creatinine (intercept) 0.0011 0.0152 −0.7
Age 0.001 0.0185 −2.1
Q1: Speech (intercept) 0.001 0.0224 2.2
Potassium (slope) 0.001 0.0136 −0.9
Onset Site: Bulbar 0.001 0.0171 −0.5
Height 0.0009 0.0169 0.8
Weight (slope) 0.0009 0.0174 −1.7
Sodium (intercept) 0.0008 0.0188 1
Bilirubin Total (intercept) 0.0008 0.0183 0.8
Sex 0.0006 0.0169 −0.4
Q10: Respiratory (slope) 0.0006 0.0153 0.8
Q4: Handwriting (slope) 0.0006 0.0206 −0.7
Weight (intercept) 0.0006 0.0181 −0.5
Q5: Cutting (intercept) 0.0002 0.0224 −4.1