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Table 3 Results of simulation study

From: joineRML: a joint model and software package for time-to-event and multivariate longitudinal outcomes

Parameter True value Mean estimated value Empirical SE Mean SE Bias MSE Coverage
D 11 0.2500 0.2411 0.0435 −0.0089 0.0020
D 21 0.0000 0.0010 0.0136 0.0010 0.0002
D 31 −0.1250 −0.1212 0.0295 0.0038 0.0009
D 41 0.0000 −0.0006 0.0127 −0.0006 0.0002
D 22 0.0400 0.0396 0.0072 −0.0004 0.0001
D 32 0.0000 −0.0002 0.0138 −0.0002 0.0002
D 42 0.0000 −0.0001 0.0055 −0.0001 0.0000
D 33 0.2500 0.2420 0.0400 −0.0080 0.0017
D 43 0.0000 0.0007 0.0134 0.0007 0.0002
D 44 0.0400 0.0399 0.0075 −0.0001 0.0001
β 0,1 0.0000 0.0028 0.0612 0.0660 0.0028 0.0038 0.9660
β 1,1 1.0000 1.0012 0.0218 0.0229 0.0012 0.0005 0.9500
β 2,1 1.0000 1.0010 0.0449 0.0470 0.0010 0.0020 0.9540
β 3,1 1.0000 0.9932 0.0897 0.0925 −0.0068 0.0081 0.9440
\(\sigma _{1}^{2}\) 0.2500 0.2506 0.0165 0.0171 0.0006 0.0003 0.9560
β 0,2 0.0000 −0.0026 0.0637 0.0655 −0.0026 0.0041 0.9660
β 1,2 −1.0000 −1.0011 0.0229 0.0223 −0.0011 0.0005 0.9480
β 2,2 0.0000 0.0008 0.0399 0.0472 0.0008 0.0016 0.9700
β 3,2 0.5000 0.5061 0.0894 0.0923 0.0061 0.0080 0.9540
\(\sigma _{2}^{2}\) 0.2500 0.2501 0.0162 0.0171 0.0001 0.0003 0.9540
γ v1 0.0000 0.0011 0.1243 0.1392 0.0011 0.0155 0.9720
γ v2 1.0000 1.0487 0.2837 0.2750 0.0487 0.0829 0.9340
γ y1 −0.5000 −0.5121 0.1936 0.2084 −0.0121 0.0376 0.9560
γ y2 1.0000 1.0311 0.2220 0.2145 0.0311 0.0502 0.9400