Fig. 1
From: Informative graphing of continuous safety variables relative to normal reference limits
Graphical View of the Untransformed RESULT Values in the MDLD dataset. a Graphical View of RESULT Values Versus Time. b Spatial Blending at the Level of the Lower Limits of Normal of the Four Testing Sites. Mock data from the MDLD dataset (RESULT variable) are plotted on the Y-axis. Time (VISIT variable) is assigned to the X-axis. Values above the ULN are marked by a blue “+”, RESULT values below the LLN are marked by a black “▼”, and values between and inclusive of the LLN and ULN are designated by an orange “
”. Reference ranges for the four sites are provided as (___) Site 1, (…..) Site 2, (_ _ _) Site 3, and (.._.._) Site 4. Note the orange dots signifying normal values are intermixed with the black inverted triangles that represent values lower than normal (see black arrows). Abbreviations – ABNFL, abnormal flag; H, abnormally high RESULT, L, abnormally low result; mg/dL, milligrams per deciliter; N, normal RESULT