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Table 3 Data available for analysis of all treatment comparisons used in intervention studies by population and study characteristics

From: Cost-effectiveness of diagnostic and therapeutic interventions for chronic hepatitis C: a systematic review of model-based analyses

  

n

Genotype 1

n (%)

Genotype 2

n (%)

Genotype 3

n (%)

Prior treatment status

Treatment Experienced

47

15 (30.61)

9 (34.62)

23 (45.1)

Treatment Naïve

79

34 (69.39)

17 (65.38)

28 (54.9)

Population

All Patients

61

27 (55.1)

13 (50)

21 (41.18)

With Cirrhosis

39

14 (28.57)

8 (30.77)

17 (33.33)

Without Cirrhosis

26

8 (16.33)

5 (19.23)

13 (25.49)

Articles

Linas, 2015

20

0 (0)

6 (23.08)

14 (27.45)

Liu, 2014

1

1 (2.04)

0 (0)

0 (0)

Najafzadeh, 2015

3

1 (2.04)

1 (3.85)

1 (1.96)

Saab, 2014

16

16 (32.65)

0 (0)

0 (0)

SanMiguel, 2014

8

2 (4.08)

2 (7.69)

4 (7.84)

Cure, 2015 (Italy)

31

14 (28.57)

8 (30.77)

9 (17.65)

Cure, 2015 (UK)

13

4 (8.16)

4 (15.38)

5 (9.8)

Pfeil, 2015

34

11 (22.45)

5 (19.23)

18 (35.29)

Treatments

SOF PEG RBV 12 wk. vs BOC PEG RBV 48 wk

14

14 (28.57)

0 (0)

0 (0)

SOF PEG RBV 12 wk. vs No Tx

7

4 (8.16)

0 (0)

3 (5.88)

SOF PEG RBV 12 wk. vs PEG RBV 24 wk

11

0 (0)

2 (7.69)

9 (17.65)

SOF PEG RBV 12 wk. vs PEG RBV 48 wk

19

13 (26.53)

0 (0)

6 (11.76)

SOF PEG RBV 12 wk. vs TEL PEG RBV 48 wk

11

11 (22.45)

0 (0)

0 (0)

SOF RBV 12 wk. vs No Tx

16

0 (0)

12 (46.15)

4 (7.84)

SOF RBV 12 wk. vs PEG RBV 24 wk

10

0 (0)

8 (30.77)

2 (3.92)

SOF RBV 12 wk. vs PEG RBV 48 wk

4

0 (0)

4 (15.38)

0 (0)

SOF RBV 24 wk. vs No Tx

22

6 (12.24)

0 (0)

16 (31.37)

SOF RBV 24 wk. vs PEG RBV 24 wk

7

0 (0)

0 (0)

7 (13.73)

SOF RBV 24 wk. vs PEG RBV 48 wk

5

1 (2.04)

0 (0)

4 (7.84)

Total

 

126

49 (38.89)

26 (20.63)

51 (40.48)

  1. Key: BOC = boceprevir; PEG = pegylated interferon; RBV = ribavirin; SOF = sofosbuvir; Tx = treatment; vs = versus; wk. = week
  2. Based on data reported in included intervention models: Cure 2015a [28], Cure 2015b [29], Linas, 2015 [37], Liu 2014 [39], Najafzadeh 2015 [41], San Miguel 2015 [47], Saab 2014 [46]