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Table 5 Quality appraisal: CHEERS checklist (intervention and surveillance models)

From: Cost-effectiveness of diagnostic and therapeutic interventions for chronic hepatitis C: a systematic review of model-based analyses

  Intervention Surveillance
CHEERS criteriaa Cure, 2015a [28] Cure, 2015b [28] Linas, 2015 [37] Liu, 2014 [39] Najfzadeh, 2015 Pfeil, 2015 [44] Saab, 2014 [46] San Miguel, 2015 [47] Canavan, 2013 [56] Crossan, 2015b [54] Liu, 2011 [57]
Q1 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q2 Unclear Yes Yes Yes Yes Yes Yes Unclear Yes Yes Yes
Q3 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q4 Yes Yes Yes No Yes Yes Yes Yes Yes Yes Yes
Q5 Yes Yes Unclear Yes Yes Yes Yes Yes Yes Yes Yes
Q6 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q7 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q8 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q9 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q10 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q11a NA NA NA NA NA NA NA NA NA NA NA
Q11b No Unclear Unclear Yes Unclear Unclear Unclear Yes Unclear Yes Unclear
Q12 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q13a NA NA NA NA NA NA NA NA NA NA NA
Q13b Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q14 No Yes Yes Yes Yes Yes Yes Unclear Yes Yes Yes
Q15 Yes Yes Unclear Unclear Yes Yes Yes Yes Yes Yes Yes
Q16 Unclear Unclear Unclear Yes Yes Unclear Unclear Unclear Yes Yes Yes
Q17 Unclear Unclear Unclear Unclear Unclear Unclear Unclear Unclear Yes Yes Yes
Q18 No Unclear Yes Unclear Yes Yes No Yes Yes Yes Yes
Q19 No Yes Yes No Yes Yes Yes Yes Yes Yes Yes
Q20 NA NA NA NA NA NA NA NA NA NA NA
Q21 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q22 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Q23 Yes Yes Yes Yes No Yes Unclear Yes Yes Yes Yes
Q24 Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
  1. Abbreviations: incl. Including, NA not applicable
  2. Notes: Studies rated unclear due to reporting omissions (incl. Where detail not reported); aCHEERS checklist criteria>#, Q1 Identify the study as an economic evaluation, Q2 Structured summary, Q3 Provide an explicit statement of the broader context for the study, Q4 Base-case population and subgroups analyzed, Q5 State relevant aspects of the system(s) in which the decision(s) need(s) to be made, Q6 Study perspective, Q7 Interventions or strategies being compared, Q8 Time horizon(s), Q9 Discount rate(s) for costs and outcomes, Q10 Outcomes measured, Q11a Single study–based estimate(s), Q11b Synthesis-based estimate(s), Q12 Population and methods used to elicit preferences for outcomes, Q13a Single study–based economic evaluation: estimation of resource use, Q13b, Model-based economic evaluation: estimation of resource use, Q14 Dates of the estimated resource quantities and unit costs, Q15 Type of decision-analytic model used, Q16 Structural or other assumptions underpinning the decision-analytic model, Q17, Analytic methods supporting the evaluation, Q18 Report the values, ranges, references, and if used, probability distributions for all parameters, Q19 Mean values for the main categories of estimated costs and outcomes of interest, as well as mean differences between the comparator groups (ICER where applicable), Q20, Single study–based economic evaluation: Effects of sampling uncertainty for estimated incremental cost, incremental effectiveness, and incremental cost-effectiveness, together with the impact of methodological assumptions (such as discount rate, study perspective), Q21 Report differences in results that can be explained by variations between subgroups, Q22 Summarize key study findings and describe how they support the conclusions reached. Limitations and generalizability of the findings; Q23, Source of funding; Q24, Conflict of interest; bModel also reported in Tsochatzis et al., 2014 [55]
  3. Sources: Intervention models included in analysis: Cure 2015a [28], Cure 2015b [29], Linas, 2015 [37], Liu 2014 [39], Najafzadeh 2015 [41], San Miguel 2015 [47], Saab 2014 [46]. Surveillance models: Canavan 2013 [56], Crossan 2015 [54], Liu 2011 [57]; Tsochatzis 2014 [55]