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Table 2 Reporting of recommended study design features in critical care medicine manuscripts 2005 and 2015 (ordinal ratings). Comparisons were made between 2005 and 2015 using Wilcoxon Rank Sum test (P-value) and proportional odds models were used to calculate odds

From: Animal experimental research design in critical care

Study design feature

Total (n = 825)

2005 (n = 482)

2015 (n = 343)

Bonferroni-adjusted P-value

Odds Ratio (98.3%CI)

Power analysis

 Not mentioned

769 (93)

464 (96)

305 (89)

< 0.0001

3.26 (1.61,6.61)

 Mentioned but not performed

16 (2)

8 (2)

8 (2)

 Performed but no details given

6 (1)

2 (0)

4 (1)

 Performed and details given

34 (4)

8 (2)

26 (8)

Randomization

 Not mentioned

445 (54)

283 (59)

162 (47)

0.0005

1.67 (1.21,2.32)

 Mentioned but not performed

50 (6)

30 (6)

20 (6)

 Performed but no details given

290 (35)

155 (32)

135 (39)

 Performed and details given

40 (5)

14 (3)

26 (8)

Blinding

 Not mentioned

596 (72)

378 (78)

218 (64)

< 0.0001

2.10 (1.45,3.04)

 Mentioned but not performed

11 (1)

8 (2)

3 (1)

 Performed but no details given

143 (17)

64 (13)

79 (23)

 Performed and details given

75 (9)

32 (7)

43 (13)