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Table 2 Reporting of recommended study design features in critical care medicine manuscripts 2005 and 2015 (ordinal ratings). Comparisons were made between 2005 and 2015 using Wilcoxon Rank Sum test (P-value) and proportional odds models were used to calculate odds

From: Animal experimental research design in critical care

Study design feature Total (n = 825) 2005 (n = 482) 2015 (n = 343) Bonferroni-adjusted P-value Odds Ratio (98.3%CI)
Power analysis
 Not mentioned 769 (93) 464 (96) 305 (89) < 0.0001 3.26 (1.61,6.61)
 Mentioned but not performed 16 (2) 8 (2) 8 (2)
 Performed but no details given 6 (1) 2 (0) 4 (1)
 Performed and details given 34 (4) 8 (2) 26 (8)
Randomization
 Not mentioned 445 (54) 283 (59) 162 (47) 0.0005 1.67 (1.21,2.32)
 Mentioned but not performed 50 (6) 30 (6) 20 (6)
 Performed but no details given 290 (35) 155 (32) 135 (39)
 Performed and details given 40 (5) 14 (3) 26 (8)
Blinding
 Not mentioned 596 (72) 378 (78) 218 (64) < 0.0001 2.10 (1.45,3.04)
 Mentioned but not performed 11 (1) 8 (2) 3 (1)
 Performed but no details given 143 (17) 64 (13) 79 (23)
 Performed and details given 75 (9) 32 (7) 43 (13)