Study design feature | Total (n = 825) | 2005 (n = 482) | 2015 (n = 343) | Bonferroni-adjusted P-value | Odds Ratio (98.3%CI) |
---|---|---|---|---|---|
Power analysis | |||||
Not mentioned | 769 (93) | 464 (96) | 305 (89) | < 0.0001 | 3.26 (1.61,6.61) |
Mentioned but not performed | 16 (2) | 8 (2) | 8 (2) | ||
Performed but no details given | 6 (1) | 2 (0) | 4 (1) | ||
Performed and details given | 34 (4) | 8 (2) | 26 (8) | ||
Randomization | |||||
Not mentioned | 445 (54) | 283 (59) | 162 (47) | 0.0005 | 1.67 (1.21,2.32) |
Mentioned but not performed | 50 (6) | 30 (6) | 20 (6) | ||
Performed but no details given | 290 (35) | 155 (32) | 135 (39) | ||
Performed and details given | 40 (5) | 14 (3) | 26 (8) | ||
Blinding | |||||
Not mentioned | 596 (72) | 378 (78) | 218 (64) | < 0.0001 | 2.10 (1.45,3.04) |
Mentioned but not performed | 11 (1) | 8 (2) | 3 (1) | ||
Performed but no details given | 143 (17) | 64 (13) | 79 (23) | ||
Performed and details given | 75 (9) | 32 (7) | 43 (13) |