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Table 1 NPC test for comparisons between CD and UC patients

From: Bonferroni-Holm and permutation tests to compare health data: methodological and applicative issues

Variables

Crohn’s disease

Ulcerative colitis

p-value

Diagnosis age

43.80 ± 21.59

45.87 ± 20.83

0.0281

Gender (M% /F%)

49.3 /50.7

57.7/42.3

0.0019

Smoking habit

43.9 /56.1

35.2 / 64.8

0.0001

Immun. therapy

38.4/61.6

26.4 / 73.6

0.0002

Duration of therapy

12.27 ± 8.67

14.92 ± 9.84

0.0032

Biological drugs (BD)

18.4/81.6

8.7/91.3

0.0004

Duration of BD

12.23 ± 7.33

16.03 ± 9.41

0.0053

Re-hospitalization

45.6 / 54.4

27.8 / 72.2

0.0008

Adverse events

17.9 / 82.1

9.2 / 90.8

0.0007

Infections

7.0/93.0

7.6 / 92.4

0.6274

Cancers

3.6 / 96.4

2.5 / 97.5

0.2755

Diabetes

5.6 / 94.4

10.6/89.4

0.0006

Hypertension

20.3 / 79.7

19.6/80.4

0.7376

Heart failure

5.7 / 94.3

5.7 / 94.3

0.9852

Kidney failure

2.1 /97.9

2.6 / 97.4

0.5074

Pulmonary failure

3.6/96.4

5.1 /94.9

0.1553

Neuropathy

1.7/98.3

1.6/98.4

0.8858

Liver disease

1.6/98.4

1.3 / 98.7

0.6075

Charlson score

1.47 ± 1.81

1.20 ± 1.39

0.0316

Surgery

19.7 /80.3

5.3 / 94.7

0.0003

Final exitus

97.9/2.1

97.6 / 2.4

0.6643

Follow-up time

34.57 ± 4.54

34.92 ± 4.16

0.0577

COMBINED p-value

  

0.0000

  1. Note: the values in italics identify the significant variables (level α = 0.05)