Retinal vascular tortuosity assessment: inter-intra expert analysis and correlation with computational measurements

Table 4 Inter-intra expert agreement analysis

Cohen-Kappa	E2_R1	E3_R1	E4_R1	E5_R1	E1_R2	E2_R2	E3_R2	E4_R2	E5_R2	V _R1	V _R2	V _{R1 R2}	R _c
E1_R1	0.39	0.53	0.57	0.61	0 . 3 5	0.39	0.22	0.20	0.66	0.92	0.35	0.57	0.53
E2_R1		0.50	0.53	0.42	0.43	0 . 5 6	0.34	0.35	0.38	0.44	0.43	0.53	0.42
E3_R1			0.43	0.48	0.44	0.50	0 . 5 0	0.33	0.52	0.59	0.51	0.70	0.74
E4_R1				0.51	0.55	0.61	0.39	0 . 4 3	0.45	0.63	0.55	0.64	0.70
E5_R1					0.37	0.51	0.31	0.25	0 . 8 3	0.69	0.45	0.71	0.57
E1_R2						0.50	0.76	0.48	0.23	0.40	0.86	0.62	0.66
E2_R2							0.48	0.48	0.46	0.44	0.64	0.69	0.73
E3_R2								0.57	0.34	0.26	0.83	0.54	0.57
E4_R2									0.28	0.22	0.61	0.43	0.46
E5_R2										0.74	0.49	0.65	0.52
V _R1											0.40	0.63	0.59
V _R2												0.70	0.74
V _{R1 R2}													0.87

Cohen-Kappa indexes for intra and inter-rater agreement as well as between each expert and V_R1, V_R2, V_R1R2 and R_c in rounds R₁ and R₂ for asymptomatic / symptomatic classification. The indexes that are highlighted in bold correspond to the intra-rater agreement between rounds R₁ and R₂

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