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Table 1 Distribution of 121 HIV genotypic mutations included in real data study according to knowledge at study time and reported in [73, 74] and number of HIV genotypic mutations selected by Lasso regularized methods

From: Lasso regularization for left-censored Gaussian outcome and high-dimensional predictors

Number of HIV genotypic mutations Gaussian BJ NonPar BJ LOD LOD/2
present in real data study     
5 in RTG probably associated 3 (60%) 3 (60%) 1 (20%) 1 (20%)
with abacavir resistance     
13 in RTG probably associated 7 (54%) 4 (31%) 4 (31%) 4 (31%)
with multi-NRTI resistance     
6 in RTG probably associated 3 (50%) 2 (33%) 1 (17%) 1 (17%)
with NRTI resistance (other than abacavir)     
30 in RTG probably associated 12 (40%) 11 (37%) 8 (27%) 7 (23%)
with NNRTI resistance     
67 in PG probably associated 40 (60%) 22 (33%) 15 (22%) 14 (21%)
with PI resistance     
121 Total 65 (54%) 42 (35%) 29 (24%) 27 (22%)