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Table 2 Reporting of clinical trial endpoints between clinical trial protocols and clinical trial registries

From: Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology

Endpoint Reporting

Trials

(%)

Endpoints

(%)

Clinical trial protocols with primary endpoints

71

 

75

 

 Primary Endpoint Discrepancies

4

(6)

4

(5)

Clinical trial protocols with secondary endpoints

71

 

507

 

 Secondary Endpoint Discrepancies

45

(63)

113

(22)

  Secondary endpoints absent from registry

36

(51)

84

(17)

   Included in published report

27

(38)

48

(9)

  Secondary endpoints absent from protocol

19

(27)

29

(6)

   Included in published report

7

(10)

9

(2)

   Present in non-endpoint section of protocol

11

(15)

14

(3)

Clinical trial protocols with exploratory endpoints

28

 

96

 

 Exploratory endpoints absent from registry

25

(89)

89

(93)