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Table 2 Reporting of clinical trial endpoints between clinical trial protocols and clinical trial registries

From: Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology

Endpoint Reporting Trials (%) Endpoints (%)
Clinical trial protocols with primary endpoints 71   75  
 Primary Endpoint Discrepancies 4 (6) 4 (5)
Clinical trial protocols with secondary endpoints 71   507  
 Secondary Endpoint Discrepancies 45 (63) 113 (22)
  Secondary endpoints absent from registry 36 (51) 84 (17)
   Included in published report 27 (38) 48 (9)
  Secondary endpoints absent from protocol 19 (27) 29 (6)
   Included in published report 7 (10) 9 (2)
   Present in non-endpoint section of protocol 11 (15) 14 (3)
Clinical trial protocols with exploratory endpoints 28   96  
 Exploratory endpoints absent from registry 25 (89) 89 (93)