Tests of trend between disease outcomes and ordinal covariates discretized from underlying continuous variables: simulation studies and applications to NHANES 2007–2008

Table 5 Conclusions of Trend Tests for the NHANES Dataset

Outcome	Method	1	2	3	4	5	6	7	8	9	10
Diabetes or Pre/Border-line	P-value	N/A	0.024	0.023	0.032	0.034	0.010	0.013	N/A	0.012	0.020
Diabetes or Pre/Border-line	Reject	N/A	Yes	Yes	Yes	Yes	Yes	Yes	N/A	Yes	Yes
High Blood Pressure	P-value	N/A	0.051	0.064	0.056	0.061	0.010	0.023	N/A	0.007	0.016
High Blood Pressure	Reject	N/A	No	No	No	No	Yes	Yes	N/A	Yes	Yes

Yes = The null hypothesis of no trend was rejected at the 0.05 significance level
No = The null hypothesis of no trend was not rejected at the 0.05 significance level
Method 1: Unweighted, no intercept
Method 2: Unweighted, with intercept
Method 3: Unweighted, with intercept, reference group omitted
Method 4: Weighted by the inverse of Var (OR), with intercept
Method 5: Weighted by the inverse of SE (OR), with intercept
Method 6: Weighted by the inverse of Var (LogOR), with intercept
Method 7: Weighted by the inverse of SE (LogOR), with intercept
Method 8: Weighted by the sample size, no intercept
Method 9: Weighted by the sample size, with intercept, reference group omitted
Method 10: Weighted by the sample size, with intercept

ISSN: 1471-2288