Baseline characteristic/Outcome | Total (N = 447) n, % |
---|---|
Months on effective regimen (mean, sd) | 11.6 (7.9) |
Ever on effective regimen | 369 (82.6) |
Sociodemographic characteristics | |
 Age, years (mean, sd) | 35.9 (11.4) |
 Female sex | 84 (18.8) |
 Married (n = 434) | 200 (46.1) |
 Unemployed (n = 445) | 352 (79.1) |
 Current or previous incarceration | 237 (53.0) |
 Alcohol abuse/dependence | 194 (43.4) |
 Illicit drug use | 79 (17.7) |
 Homelessness | 16 (3.6) |
Comorbidities | |
 HIV-positive (n = 446) | 3 (0.7) |
 Diabetes mellitus (n = 446) | 18 (4.0) |
 Comorbid condition | 322 (72.0) |
Prior TB treatment exposure | |
 Previously treated for TB | 444 (99.3) |
 History of prior injectable exposure (n = 436) | 145 (33.3) |
 History of prior fluoroquinolone exposure (n = 436) | 69 (15.8) |
 History of prior default | 16 (3.6) |
 Number of previous TB treatments (mean, sd) | 2.1 (1.2) |
 > 2 previous TB treatment (n = 436) | 141 (32.3) |
Clinical indications of disease severity | |
 Bilateral and cavitary disease on baseline chest x-ray (n = 443) | 278 (62.8) |
 Severe pulmonary disease on baseline chest x-ray | 195 (43.6) |
 Low BMI at start of treatment (n = 446) | 190 (42.6) |
 Severe baseline clinical status | 277 (62.0) |
 Extrapulmonary disease (n = 381) | 39 (10.2) |
 Previous TB-related surgery (n = 445) | 50 (11.2) |
 Baseline XDR-TB | 22 (4.9) |
Initial treatment outcome | |
 Successful | 299 (66.9) |
 Cure | 280 (62.6) |
 Treatment Completion | 19 (4.3) |
 Unsuccessful | 148 (33.1) |
 Death | 30 (6.7) |
 Treatment Failure | 39 (8.7) |
 Default | 78 (17.4) |
 Transfer Out | 1 (0.2) |