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Fig. 8 | BMC Medical Research Methodology

Fig. 8

From: An application of a pattern-mixture model with multiple imputation for the analysis of longitudinal trials with protocol deviations

Fig. 8

Prednisolone reference arm (Treatment = 1): Profile plots of the mean \(\sqrt {\text {CD4}}\) count against month for the four different deviation patterns. The solid lines join the observed means (before deviation) and the dotted lines join the means of the imputed data for that pattern. Pattern 4: group of patients who completed the study (completers), Pattern 3: group of patients who dropped out after month 3, Pattern 2: group of patients who dropped out after month 1 and Pattern 1: group of patients who dropped out after week 2

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