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Table 6 MCAR mechanism by missingness rate

From: An application of a pattern-mixture model with multiple imputation for the analysis of longitudinal trials with protocol deviations

Missingness rates   Treatment Time Treatment x Time Coverage probability
5% Analysis Bias RMSE Bias RMSE Bias RMSE Treatment Time Treatment x Time
  ML -0.063 0.127 -0.005 0.015 0.028 0.033 94.10% 96.40% 93.50%
  MI -0.0602 0.127 0.001 0.020 0.021 0.031 95.50% 94.10% 95.80%
  LMCF -0.079 0.137 -0.049 0.051 0.032 0.039 93.50% 95.00% 95.60%
  J2R (P-) -0.100 0.149 -0.006 0.016 0.050 0.054 92.70% 95.40% 94.30%
  CDR (P-) -0.090 0.141 -0.006 0.016 0.040 0.046 93.10% 95.30% 94.20%
  CR (P-) -0.095 0.146 -0.006 0.016 0.045 0.050 92.20% 95.30% 94.80%
10%           
  ML 0.112 0.157 -0.017 0,022 0.028 0.035 89.50% 94.50% 95.00%
  MI 0.112 0.158 -0.018 0.024 0.030 0.040 90.50% 95.50% 95.00%
  LMCF 0.095 0.150 -0.103 0.104 0.040 0.046 92.50% 87.50% 95.50%
  J2R (P-) 0.072 0.133 -0.015 0.020 0.054 0.058 94.5% 87.50% 94.50%
  CDR (P-) 0.088 0.143 -0.015 0.020 0.046 0.051 92.50% 86.50% 96.00%
  CR (P-) 0.078 0.136 -0.015 0.020 0.052 0.057 93.50% 88.50% 95.50%
20%           
  ML -0.032 0.12 -0.0024 0.017 0.024 0.034 95.00% 94.50% 95.00%
  MI -0.042 0.124 -0.005 0.022 0.033 0.045 94.50% 95.50% 95.00%
  LMCF -0.099 0.154 -0.183 0.183 0.078 0.083 93.50% 90.50% % 94.50%
  J2R (P-) -0.122 0.164 0.0002 0.016 0.092 0.100 89.50% 95.00% 94.50%
  CDR (P-) -0.074 0.134 0.0002 0.016 0.057 0.063 95.50% 95.00% 93.50%
  CR (P-) -0.099 0.149 0.0002 0.016 0.073 0.075 94.50% 95.00% 94.50%
30%           
  ML -0.092 0.149 -0.052 0.055 0.043 0.051 94.30% 94.50% 95.10%
  MI -0.050 136 -0.030 0.039 0.005 0.037 94.40% 95.20% 95.80%
  LMCF -0.136 0.184 -0.279 0.280 0.081 0.086 89.10% 85.70% 90.20%
  J2R (P-) -0.220 0.252 -0.059 0.062 0.138 0.141 85.20% 94.50% 87.40%
  CDR (P-) -0.160 0.200 -0.059 0.062 0.094 0.098 90.50% 94.10% 95.30%
  CR (P-) -0.197 0.216 -0.059 0.062 0.109 0.112 90.90% 93.20% 92.70%
50%           
  ML 0.036 0.123 0.0004 0.022 0.009 0.033 96.60% 95.30% 95.40%
  MI 0.039 0.136 -0.006 0.031 0.026 0.051 95.30% 95.10% 94.60%
  LMCF -0.045 0.129 -0.360 0.360 0.084 0.088 94.30% 89.10% 95.40%
  J2R (P-) -0.112 0.159 0.0004 0.023 0.127 0.130 89.50% 95.10% 90.60%
  CDR (P-) -0.045 0.121 0.0004 0.023 0.088 0.089 94.70% 95.20% 93.40%
  CR (P-) -0.087 0.142 0.0004 0.023 0.112 0. 115 91.20% 95.20% 89.50%