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Table 1 Summary of characteristics of articles

From: A scoping review of the problems and solutions associated with contamination in trials of complex interventions in mental health

Variable

Level

Number of articles

Type of article (n)

Results of primary analysis of clinical trial

228 (97.4%)

Design / protocol of clinical trial

3 (1.3%)

Results of secondary analysis of clinical trial

3 (1.3%)

Year (n)

2000–2004

47 (20.0%)

2005–2009

85 (36.3%)

2010–2015

102 (43.6%)

Country of origin (n)

USA

101 (43.2%)

UK

39 (16.7%)

Netherlands

19 (8.1%)

Canada

14 (6.0%)

Australia

11 (4.7%)

Other

50 (21.4%)

Target population (n)

Adult patients

172 (73.5%)

Children / adolescent patients

45 (19.2%)

People at risk

5 (2.1%)

Workers

12 (5.1%)

Target condition (n)

Depression

30 (28.6%)

Substance abuse

18 (17.1%)

Psychosis

14 (13.3%)

Neurodegeneration

13 (12.4%)

Anxiety

6 (5.7%)

Attention deficit hyperactivity disorder

5 (4.8%)

Others

19 (18.1%)

Intervention (n)

Cognitive behavioural therapy / CBT skills

33 (14.1%)

Care management / interdisciplinary care

26 (11.1%)

Education

21 (9.0%)

Motivational interviewing / motivational enhancement therapy

19 (8.1%)

Other psychotherapy / counselling

16 (6.8%)

Assessment and feedback

8 (3.4%)

Parenting interventions

8 (3.4%)

Others

103 (44.0%)

Phase (n)

Early (pilot and feasibility trials)

29 (12.4%)

Late

205 (87.6%)

Level of treatment allocation (n)

Participant level

141 (60.3%)

Cluster level

93 (39.7%)

Sample size (median; IQR)

Participant-level allocation

143 (84–261)

Cluster-level allocation

285 (158–579)

Cluster size in cRCTs (median; range)

 

10 (3–200)