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Table 2 Correlation between serogroup-polysaccharide specific IgG levels and functional antibody titers (rSBA) in serum measured before (T0), one month (T1) and one year (T2) after the vaccination

From: Use of saliva to monitor meningococcal vaccine responses: proposing a threshold in saliva as surrogate of protection

Serogroup

T0 R (95% CI), p-value

T1 R (95% CI), p-value

T2 R (95% CI), p-value

All R (95% CI), p-value

MenA

0.11 (āˆ’ā€‰0.03ā€“0.24), 0.14

0.34 (0.22ā€“0.46), <ā€‰0.001

0.26 (0.13ā€“0.39), 0.002

0.78 (0.75ā€“0.81), <ā€‰0.001

MenC

0.64 (0.58ā€“0.69), <ā€‰0.001

0.82 (0.78ā€“0.85), <ā€‰0.001

0.84 (0.81ā€“0.86), <ā€‰0.001

0.96 (0.96ā€“0.97), <ā€‰0.001

MenW

0.01 (āˆ’ā€‰0.13ā€“0.15), 0.85

0.23 (0.09ā€“0.35), 0.0013

0.29 (0.16ā€“0.41), <ā€‰0.001

0.74 (0.70ā€“0.77), <ā€‰0.001

MenY

0.24 (0.11ā€“0.38), 0.001

0.19 (0.05ā€“0.32), 0.007

0.25 (0.12ā€“0.38), 0.001

0.76 (0.72ā€“0.79), <ā€‰0.001

  1. Note. Abbreviations: R Pearson correlation coefficient, CI confidence interval