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Table 4 Estimated threshold for salivary IgG, true positive rate (TPR), false positive rate (FPR), positive predictive value (PPV) and negative predictive value (NPV) with ROC curve analysis with a functional antibody titer (rSBA) >=128 as correlate of protection

From: Use of saliva to monitor meningococcal vaccine responses: proposing a threshold in saliva as surrogate of protection

Serogroup

Threshold (ng/mL)

TPR

FPR

PPV

NPV

MenC

3.54

0.86

0.10

0.95

0.74

MenW

2.00

0.62

0.09

0.94

0.50

MenY

1.82

0.51

0.09

0.95

0.36