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Table 1 Empirical results for the averages of the relative bias (r.Bias) and standard errors (SEM), standard deviation (SD), and coverage probability (CP) for the regression parameters and variance parameter of the log-normal frailty based on the ‘imputed-by-the-right-endpoint’ and ‘proposed’ methods when the type of regression coefficients is ‘even’ under three types of LTF proportions (‘low’, ‘moderate’, and ‘high’)

From: Additive-multiplicative hazards regression models for interval-censored semi-competing risks data with missing intermediate events

  

Low (LTF(%)=22.6)

Moderate (LTF(%)=34.2)

High (LTF(%)=47.3)

Parameter

True value

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

  

Imputed-by-the-right-endpoint method

α 01

0.01

81.7

15026

15104

96.8

73.3

15105

14975

95.2

20.6

14450

15186

96.2

α 02

0.01

176.2

22297

22961

95.4

324.5

24408

24066

94.8

28.8

27643

27426

95.4

α 03

0.01

133.2

27006

26429

95.4

86.1

16223

17086

96.2

75.3

13291

13250

95.2

α 12

0.01

-145.7

28481

25849

95.2

-113.4

29996

26279

93.6

74.1

27309

25620

96.2

α 32

0.01

109.7

65489

55615

93.2

77.1

36087

33747

96.8

50.8

26680

25219

94.8

β 01

0.004

-10.1

81

87

93.8

-9.4

80

88

91.6

-8.6

87

88

92.6

β 02

0.004

1.1

92

92

94.6

-1.4

97

96

94.4

-0.4

103

101

94.0

β 03

0.004

-7.2

87

86

91.2

-6.4

105

105

93.4

-9.3

136

133

91.6

β 12

0.004

3.5

115

115

97.0

5.7

112

116

95.6

3.4

116

115

95.8

β 32

0.004

-0.3

217

199

96.8

7.6

174

173

96.4

5.3

148

152

97.2

σ 2

0.01

904.5

8164

8782

93.8

815.5

7848

8084

92.4

771.6

7626

7076

90.4

  

Proposed method

α 01

0.01

32.2

15236

15136

96.2

64.8

15344

15084

95.0

20.7

14496

15279

96.2

α 02

0.01

70.2

22692

22951

95.0

286.1

24010

24133

95.2

100.4

28030

27569

95.2

α 03

0.01

289.4

27525

26349

95.0

121.3

16740

17161

95.0

86.3

13465

13391

95.0

α 12

0.01

-24.6

26718

25661

95.8

-83.4

29355

26230

94.0

-37.0

27102

25736

96.2

α 32

0.01

123.2

67188

56122

93.6

93.4

36291

33577

95.6

54.0

26591

25204

94.2

β 01

0.004

-5.5

89

90

95.0

-5.0

85

91

93.8

-5.3

88

91

94.4

β 02

0.004

5.9

95

97

96.2

4.0

99

100

94.2

4.8

107

106

94.8

β 03

0.004

-1.7

92

91

93.2

-1.7

107

110

95.6

-3.3

141

139

93.4

β 12

0.004

-1.9

109

110

96.4

0.9

108

112

95.2

0.1

110

111

96.0

β 32

0.004

1.0

214

199

96.6

8.4

179

175

96.2

4.4

150

153

97.0

σ 2

0.01

1016.2

9069

9074

92.2

897.8

7743

8198

91.0

874.1

7616

7423

87.2