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Table 3 Meta-analytic simulation results (1000 replications)

From: Assessing correlates of protection in vaccine trials: statistical solutions in the context of high vaccine efficacy

Model V E mean (R2) median(R2) Std (R2) 95%ll 95%ul MSE (R2)
Logistic 0.75 0.59 0.61 0.16 0.24 0.84 0.12
Firth 0.75 0.72 0.73 0.09 0.54 0.86 0.04
WIP 0.75 0.71 0.72 0.09 0.51 0.85 0.05
Logistic 0.82 0.52 0.54 0.22 0.03 0.85 0.19
Firth 0.82 0.73 0.75 0.09 0.52 0.87 0.04
WIP 0.82 0.71 0.72 0.10 0.48 0.87 0.05
Logistic 0.9 0.46 0.49 0.26 0.01 0.86 0.26
Firth 0.9 0.72 0.74 0.10 0.48 0.88 0.04
WIP 0.9 0.70 0.71 0.11 0.45 0.87 0.05
  1. Estimated R2 (mean, median, standard error, 95% confidence intervals and MSE) for different models and values of VEs