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Table 4 Adjusted models explaining variance in WHOQOL-BREF domains

From: Performance of the WHOQOL-BREF among Norwegian substance use disorder patients

Variables with significant main effects or interaction effects ß p R2
Physical health QoLa    0.590
 Depression score −8.0 0.001  
 Unemployment −26.9 0.048  
 Social isolation * smoking −32.4 0.040  
 Social isolation * residential treatment −20.2 0.034  
 Social isolation * weight dissatisfaction −16.6 0.026  
Psychological health QoLb    0.524
 Depression score −11.9 < 0.001  
 Single −9.4 0.037  
Social relationships QoLc    0.271
 Depression score −14.3 0.001  
Environment QoLd    0.386
 Depression score −7.2 0.043  
 Social isolation * no cannabis −27.0 0.036  
 Social isolation * exercise −19.6 0.004  
 Exercise * no amphetamines + 26.8 0.003  
  1. QoL Quality of life
  2. Not significant in adjusted models, after stepwise inclusion: aunemployment, smoking, physical inactivity, weight dissatisfaction, benzodiazepine use, opioid maintenance treatment cohort. bpartner status, living situation. csocial isolation. demployment, psychiatric services received, social isolation, chronic disease, physical activity, polysubstance use, cannabis use, amphetamine use
  3. Depression and social factors, rather than the direct effects of substance use or severity, explained most of the variance of the physical health and psychological health QoL domains of the WHOQOL-BREF