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Fig. 5 | BMC Medical Research Methodology

Fig. 5

From: Sample size calculation for estimating key epidemiological parameters using serological data and mathematical modelling

Fig. 5

Optimal allocation (N = 3300) for various epidemiological parameters and by model (y-axis) among the six age groups (with lighter shades with increasing age group): [1,2), [2,6), [6,12), [12,19), [19,31), and [31,65] years, varicella-zoster virus (top) and parvovirus B19 (bottom) serological data. MSIR pcw: MSIR model with piecewise constant force of infection; Exp. damped: exponentially damped model; MSIRWb-ext AW: Maternally-derived immunity-Susceptible-Infectious-Recovered model allowing for age-specific waning of disease-acquired antibodies and boosting of low immunity; f.o.i: force of infection; Prev: prevalence

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