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Table 3 Simulated TIE and power of the proposed two-stage minimax and optimal designs in Table 2

From: Two-stage optimal designs with survival endpoint when the follow-up time is restricted

   Minimax design Optimal design
Power θ TIE Power TIE Power
90% 15 0.040 (0.036,0.044) 0.907 (0.901,0.913) 0.037 (0.033,0.041) 0.903 (0.898,0.909)
95% 15 0.041 (0.037,0.045) 0.957 (0.953,0.961) 0.038 (0.035,0.042) 0.955 (0.951,0.959)
90% 30 0.040 (0.037,0.044) 0.911 (0.905,0.916) 0.039 (0.035,0.043) 0.910 (0.904,0.916)
95% 30 0.042 (0.038,0.046) 0.959 (0.955,0.963) 0.040 (0.036,0.044) 0.958 (0.954,0.962)
90% 50 0.041 (0.037,0.045) 0.911 (0.905,0.916) 0.040 (0.037,0.044) 0.909 (0.903,0.914)
95% 50 0.042 (0.038,0.046) 0.960 (0.956,0.963) 0.041 (0.037,0.045) 0.959 (0.955,0.963)
  1. The 95% confidence intervals for the parameters of interest are computed using 1000 simulations where 10,000 designs are simulated in each simulation