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Missing outcome data balanced in numbers across intervention groups, with similar reasons for missing data across groups
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There is no quantitative measure of “balanced”
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For dichotomous outcome data, the proportion of missing outcomes compared with observed event risk not enough to have a clinically relevant impact on the intervention effect estimate
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There is no quantitative measure of “not enough”
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Missing data have been imputed using appropriate methods
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Not specified what is considered by Cochrane to be “appropriate methods”
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Reason for missing outcome data likely to be related to true outcome, with either imbalance in numbers or reasons for missing data across intervention groups
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There is no quantitative measure of “imbalance”
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Potentially inappropriate application of simple imputation.
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Not specified what is considered to be “inappropriate application”
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