A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

Table 4 Population risk differences (PRDs) for cumulative metabolic outcomes (N = ∑_jY^j)

	PRD^a (95% credible interval)^b
	Adjusted (including WBC count)		Adjusted (without WBC count)
N ≥ 1
LD/CRT	0.15	(0.02, 0.27)	0.14	(0.02, 0.26)
HD/CRT	0.11	(−0.05, 0.26)	0.10	(−0.05, 0.24)
N ≥ 2
LD/CRT	0.11	(−0.01, 0.22)	0.12	(0.01, 0.23)
HD/CRT	0.05	(−0.08, 0.19)	0.07	(−0.05, 0.20)
N ≥ 3
LD/CRT	0.04	(−0.01, 0.10)	0.05	(−0.00, 0.11)
HD/CRT	0.03	(−0.03, 0.09)	0.04	(−0.01, 0.11)
N = 4
LD/CRT	0.01	(−0.00, 0.02)	0.01	(−0.00, 0.02)
HD/CRT	0.01	(−0.00, 0.02)	0.01	(−0.00, 0.02)

Point estimates are posterior means based on 10,000 draws. LD low-dose corticosteroids, HD high-dose corticosteroids, CRT cranial radiotherapy, WBC white blood cell. ^a: The baseline treatment level is LD/No CRT. ^b: Endpoints are 2.5 and 97.5 empirical percentiles

ISSN: 1471-2288