Prior medication adherence of participants and non participants of a randomized controlled trial to improve patient adherence in cardiovascular risk management

Table 1 Differences in patient characteristics between participants and non participants in a RCT-trial on adherence

	Participants [n = 419]	Non-participants [n = 481]	P-value
Age [mean, ±SD)	60.5 [±10]	63 [11]	0.001
Gender (N [%])
Male	296 [7]	279 [58]	< 0.001
Female	123 [29	202 [42]	< 0.001
Education level (N[%])			< 0.001
Primary	66 [18]	141 [31]
Secondary	185 [49]	180 [39]
University	124 [33]	140 [30]
Labour (N[%])			0.08
Paid labour	137 [37]	123 [27]
Unemployed	98 [26.3]	138 [30]
Retired	138 [37]	199 [43.3]
Country of origin is the Netherland (N[%])			0.66
Yes	327 [90]	398 [86]
No	37 [10]	64 [14]
Reason referral (N[%])			< 0.001
acute coronary syndrome	150 [36]	79 [16]
peripheral arterial disease	71 [17]	101 [21]
troke/TIA	198 [47]	301 [63]
Blood pressure (mmHg; mean ± SD)			< 0.001
Systolic	136 [±18]	142 [±20]	0.23
Diastolic	77 [±11]	78 [±11]	0.23
Body Mass Index (mean ± SD)	27 [±4]	26 [±4]	0.30
Waist (mean ± SD)
Male	99.5 [±9]	98.4 [±12]	0.10
Female	92 [±14]	90 [±13]	0.07
Lipids (mmol/ltr, mean SD)
Totaal cholesterol	4.5 [±1.1]	4.6 [±1]	0.7
Triglyceriden	1.8 [±1]	1.7 [±1]	0.01
HDL	1.2 [±0.3]	1.2 [±0.3]	0.002
LDL	2.5 [±0.9]	2.6 [±0.9]	0.66
Medication (N [%])
Antithrombotic agents [ATC B01]	404 [98]	461 [98]	0.78
Diuretics [ATC C03]	109 [26]	135 [29]	0.44
Beta Blocking agents [ATC C07]	239 [58]	218 [46]	0.001
Calcium channel blockers [ATCC08]	65 [16]	72 [15]	0.86
Agents acting on [..] system [ATC C09]	244 [59]	206 [44]	0.001
Lipid modifying agents [ATC C10]	387 [94]	384 [82]	< 0.001

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