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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: a simulation study

Fig. 2

The baseline hazard function for recrudescence and new infection used for simulation study II. Top panel (recrudescence); bottom (new infection). Drug A (orange) is the reference arm and its hazard function for recrudescence and new infection is kept constant across all the simulation scenarios studied. Drug B (green) is a new regimen which is being compared against drug A. Scenario 1 (1A, 1B and 1C) is the null scenario where there is no difference in hazard function of recrudescence between these two drugs. In scenario 2, the two regimens have same hazard function for new infection, but drug B has either increased or decreased hazard of recrudescence with respect to drug A. In scenario 3, the two drugs differ in terms of both recrudescence and new infection

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BMC Medical Research Methodology

ISSN: 1471-2288

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