Table 1 Different scenarios for comparing two drug regimens (drug B compared against drug A) in simulation study II

1

Drug B has same effect on RC as Drug A, and

 1A

Drug B has same effect on NI

 1B

Drug B Increases NI

 1C

Drug B Decreases NI

2

Drug B has same effect on NI as Drug A, and

 2A

Drug B increases RC

 2B

Drug B decreases RC

3

Drug B has different effect on both RC and NI relative to Drug A, and

 3A

Drug B increases RC and increases NI

 3B

Drug B increases RC and decreases NI

 3C

Drug B decreases RC and increases NI

 3D

Drug B decreases RC and decreases NI