Fig. 6
From: Sequence symmetry analysis graphic adjustment for prescribing trends
The lower curves of Figures a and b show the prescribing trend for exclusive components—true trend—and the upper curves show the prescribing trend for all components. In this example, using all components resulted in a differential change in shape between respective WTDs owing to the change in shape of the distribution at Figure a. For little or no change in shape between WTDs, both curves should run close to parallel within each WTD. (The two-year gap at the beginning of the WTDs indicates that fist supply times took extra time to settle down to where they could be used for reliable follow-up)